Do cartridges need to be brought to room temperature before use? March 03, 2021 19:22 No, cartridges can be used directly out of refrigeration. Related articles Do I need to calibrate my binx io Instrument? What printer can I use with my binx io? How does the binx io System compare to its competitors? What should I do if I receive an invalid result? How do I clean my binx io Instrument?